Detalhe da pesquisa
1.
Addendum: MCC950 closes the active conformation of NLRP3 to an inactive state.
Nat Chem Biol
; 17(3): 361, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33495649
2.
Evolutionary analyses of the gasdermin family suggest conserved roles in infection response despite loss of pore-forming functionality.
BMC Biol
; 20(1): 9, 2022 01 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34996441
3.
Characterization of Novel Pathogenic Variants Leading to Caspase-8 Cleavage-Resistant RIPK1-Induced Autoinflammatory Syndrome.
J Clin Immunol
; 42(7): 1421-1432, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35716229
4.
MCC950 closes the active conformation of NLRP3 to an inactive state.
Nat Chem Biol
; 15(6): 560-564, 2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31086329
5.
Techniques to Study Inflammasome Activation and Inhibition by Small Molecules.
Molecules
; 26(6)2021 Mar 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-33803783
6.
Correction to: Characterization of Novel Pathogenic Variants Leading to Caspase-8 Cleavage-Resistant RIPK1-Induced Autoinflammatory Syndrome.
J Clin Immunol
; 42(7): 1433, 2022 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-35802274
7.
Pathogenic NLRP3 mutants form constitutively active inflammasomes resulting in immune-metabolic limitation of IL-1ß production.
Nat Commun
; 15(1): 1096, 2024 Feb 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-38321014
8.
Evolution of the gasdermin family and pyroptosis.
Dev Comp Immunol
; 149: 105060, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37734430
9.
Measuring NLR Oligomerization III: Detection of NLRP3 and NLRC4 Complex by Bioluminescence Resonance Energy Transfer.
Methods Mol Biol
; 2696: 93-103, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37578717
10.
Physiological and pathophysiological functions of NLRP6: pro- and anti-inflammatory roles.
Commun Biol
; 5(1): 524, 2022 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35650327
11.
NLRP3 Inflammasome and Pyroptosis in Liver Pathophysiology: The Emerging Relevance of Nrf2 Inducers.
Antioxidants (Basel)
; 11(5)2022 Apr 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-35624734
12.
Soluble P2X7 Receptor Is Elevated in the Plasma of COVID-19 Patients and Correlates With Disease Severity.
Front Immunol
; 13: 894470, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35663992
13.
Sensing low intracellular potassium by NLRP3 results in a stable open structure that promotes inflammasome activation.
Sci Adv
; 7(38): eabf4468, 2021 Sep 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-34524838
14.
RACK1 Mediates NLRP3 Inflammasome Activation by Promoting NLRP3 Active Conformation and Inflammasome Assembly.
Cell Rep
; 33(7): 108405, 2020 11 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-33207200
15.
P2X7 receptor induces mitochondrial failure in monocytes and compromises NLRP3 inflammasome activation during sepsis.
Nat Commun
; 10(1): 2711, 2019 06 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-31221993
16.
NLRP3 lacking the leucine-rich repeat domain can be fully activated via the canonical inflammasome pathway.
Nat Commun
; 9(1): 5182, 2018 12 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30518920